Ethslọ ndị na-emepụta mkpụrụ ndụ cellulose gbanwee nke nwere ezigbo ihe dị ka ezigbo mmiri solivation, akụrụngwa na-emepụta ihe, na-ejikwa ụlọ ọrụ ọgwụ. N'ihi ezigbo ya biocom dị mma biocom dị mma na nchekwa, ndị eyers cellougul na-arụ ọrụ dị mkpa na-akwado ọgwụ.
1. Ihe matriks maka nhazi nke a na-achịkwa
N'ime ụlọ ọrụ ọgwụ, nkwadebe na-achịkwa bụ klaasị nke ọgwụ na-eme ka nrụpụta ọgwụ na-adị ogologo oge nrụpụta nke ọgwụ ọjọọ site na ịchịkwa ọgwụ ọgwụ. A na-ejikarị usoro ndị na-eme ihe dị ka ihe matriks maka nkwadebe ma na-achịkwa ya n'ihi akụrụngwa anụ ahụ ha pụrụ iche. Hydroxypyl Methylcelllose (HPMC) bụ otu n'ime eyers cellumose niile. Ọ nwere ike mepụta gel na mmiri ma nwee ike ịchịkwa ọnụego ọgwụ ọgwụ. Site na idozigharị viscosity, ogo nke dochie na ọdịnaya nke cellose ether na nkwadebe, enwere ike idozi ụdị ọgwụ ahụ dị ka achọrọ. Nke a na-eme ka a na-azọpụta matriks ezigbo matriks maka ịtọhapụ, a na-achịkwa ya na nkwadebe ma hapụ ya.
2. Ndị na-eme mkpọtụ mbadamba
Na mmepụta nke mbadamba, enwere ike iji usoro cellususe dị ka ndị na-eme ihe iji hụ na nkesa nke ọgwụ na ike nke mbadamba. Karịsịa na mgbochi mmiri, sodium celloxythythythythythythythythythythythylythyl na-ejikarị igwe na-eme ihe, nke nwere ike ịkwalite nraranye nke irighiri ihe, si otú ahụ na-enyere ndọtị na nkwụsi ike nke mbadamba. Na mgbakwunye, ntinye nke mkpụrụ ndụ na mbadamba nwekwara ike imeziwanye nkewa nke mbadamba, ka ọgwụ ndị a tọhapụrụ na anụ ahụ ma melite bioavailality.
3. Ihe nkiri mkpuchi
A na-ejikarị ndị na-eme ihe na-eme ọtụtụ ebe a na-edebe akwụkwọ nri. Dị ka ihe mkpuchi, hydroxylthylthylthyl na-eme ezigbo ihe nkiri na-akpụ akpụ akpụ akpụ ma nwee ike melite nkwụkasị, mmiri na-eguzogide na ọdịdị nke mbadamba ọgwụ ike. Fills Ewed fim nwekwara ike igbu oge ntọhapụ ọgwụ iji mezuo ma ọ bụ mmetụta aka. Na mgbakwunye, site na ijikọta ndị ọzọ na-enupụ mkpụrụ, enwere ike iji ọrụ dị iche iche, dị ka mkpuchi ngwa ngwa, nke a na-ejide onwe ya, wdg, iji gboo mkpa nke ọgwụ dị iche iche.
4. Ndị na-eme mkpọtụ ma kwụrụ
Na mmiri mmiri na-akwado, emulsions na nkwụsị, ụgbụ mkpụrụ ndụ cellosuse na-arụ ọrụ dị mkpa dị ka ndị na-eme ihe. Ọ nwere ike iwelie viscosict nke ihe ngwọta ma melite nkwusioru ọgwụ ahụ, si otú a hụ na otu na nkwụsi ike nke ọgwụ. For example, in ophthalmic preparations and oral suspensions, sodium carboxymethyl cellulose as a thickener can improve the adhesion and stability of the drug during use. Na mgbakwunye, evers celluse na-arụ nke ọma n'ihe banyere biocompatibility, ọ naghị akpata iwe ma ọ bụ mmeghachi omume nfụkasị, nke na-eme ha nke ọma na ọgwụ ọgwụ Ophtholmic.
5. Ihe eji eme mgbidi maka akwa nhicha
A na-emekwa ka e nwere ike iji ya dị ka ihe akụrụngwa maka nkwadebe capsule, ọkachasị na nkwadebe nke capsules nke osisi. Ihe ọdịbetị ahụ ọdịnala bụ tumadi, mana ya na mmụba nke ndị na-eri nri na ndị na-anụ ufe, ọchịchọ maka ihe ndị a kụrụ na nke nta nke nta na-eto. Ethslọ ekike celllugul dị ka hydropyylthylthyl methylcelllose abụrụla ihe dị mkpa nke capsules nke ahịhịa. Typedị capsule a abụghị naanị na-enwe ezigbo solig, kamakwa ọ na-enye ike nke na-enweghị ike, na-enwe mkpa nke ndị na-eri nri na ndị nwere mmetụta maka ọgwụ mgbochi ọgwụ.
6. Ngwa na ọnụego na-akwado
A na-ejikwa ndị Ether na-ejikarị ya na-eme ọtụtụ ihe. N'ihi ezigbo adhesion na biocompative, eyers cell nwere ike ịmalite ihe nkiri nchebe na oghere a ga-echebe ma ọ bụ elu anụ ahụ nke ọma, na-eme ka oge nsị nke ọgwụ ọjọọ na saịtị. Iji maa atụ, na iji mee ka mbadamba nkume, nhicha na mmanụ otite, eyers nwere ike ịrụ ezigbo ọrụ dị ka ndị na-akpata ọgwụ ọjọọ.
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A na-ejikwa ụkpụrụ mkpụrụ osisi cellulose mee ihe maka owuwu microciences na usoro nnyefe ọgwụ ọjọọ. Mgbe a na-ejikarị microcpapes ma ọ bụ nanopartics, a na-ejikarị ndị na-eme mkpọtụ dị ka ihe eji eme mgbidi ma ọ bụ ndị na-ebu ihe iji mezuo ma ọ bụrụ na a na-achịkwa ya ma ọ bụrụ na a na-ebugharị ya ma ọ bụrụ na a na-ebugharị ya ma ọ bụrụ na a na-enyefe ya ma ọ bụrụ na ha na-achịkwa ya. For example, hydroxypropyl methylcellulose and carboxymethyl cellulose play an important role in the preparation of long-acting microencapsulated drugs. Eutterslọ ọrụ mkpụrụ ndụ cellugul enweghị ike ichebe ọgwụ ọjọọ site na nsonaazụ eriri afọ, kamakwa ọ na-adị ogologo ọgwụ nke ọgwụ ọjọọ site na ịhazi usoro ntọhapụ.
A na-ejikarị ndị na-eme ihe na-eme ọgwụ ọtụtụ ebe, na-ekpuchi ọtụtụ ubi site na nkwalite ọgwụ, na-eme ka ọ kpọọ ọrụ na-adịghị mma na mmepe nke nkwadebe ọgwụ. Na mmepe na teknụzụ ọgwụ na-aga n'ihu, ngwa ọrụ nke usoro nke usoro nnyefe mkpụrụ osisi, ọgwụ ngụgụ na biodicine, ndị Eyed Cell Cell ga-aga n'ihu na-arụ ọrụ dị mkpa.
Oge post: Feb-17-2025