Ngwa nke hydroxyppropyyththththththththylcellose na ụlọ ọrụ ọgwụ

Hypromellose (HPMC) bụ ihe na-enye ihe na-emepụta mkpụrụ osisi nke na-eme ihe n'ọtụtụ ebe n'ihi ezigbo ọrụ ọrụ ya na biocom. Mpaghara ngwa ya gụnyere ndị na-eji bọọdụ mbadamba, ihe ndị na-akụ, mkpuchi, mkpuchi, na nkwadebe nke ọgwụ na gels.

1. Binders

Na Nmepụta Mbadamba ụrọ, HPMC dị ka ihe mgbochi nwere ike ịkwalite ike ọgwụ na-eme ka ọ bụrụ nke ọgwụ - na-eme ka ha nwee mbadamba nkume kwụsiri ike n'oge table. HPMC Binders nwere uru ndị na-esonụ:
Ngwaọrụ nke igwefoto HPMC guzobere ike na mbadamba ihe na-enyere aka mee ka ike nke mbadamba ahụ ma belata ihe ize ndụ nke mkpirisi.
Ekelite Unifornity: N'ihi ezigbo sọlị ya na mmiri, enwere ike kesara Hpmc n'elu mmiri iji hụ na ọgwụ ọgwụ na-agbanwe agbanwe na mbadamba ihe ọ bụla.
Nkwụsị: HPMC na-egosi nkwụsi ike n'okpuru ọnọdụ okpomọkụ na ọnọdụ iru mmiri, ma nwee ike ịnọgide na-enwe ihe owuwu mbadamba mgbe ọ na-adịkarị ike gburugburu ebe obibi.

2. Ndị na-agbasa

Ọrụ nke ịgbasa bụ ime ka mbadamba belata ngwa ngwa mgbe ịkpọtụrụ mmiri mmiri iji hapụ ihe ndị ọgwụ. HPMC nwere ike ịkwalite mbadamba mbadamba nke ọma n'ihi Njirimara ọzịza:
Hydrotion na-abata: Mgbe HPMC na-abata na mmiri, ọ ga-anyụ mmiri ngwa ngwa ma zaa ya, na-eme ka ihe ndị ahụ na-eme ka ọ bụrụ ihe na-atọ ụtọ.
Oge a na-agbanwe agbanwe: Site na ịhazigharị viscosity nke HPMC, nke na-enweghị atụ nke mbadamba mbadamba nke ọma iji mezuo ihe ngbanwe nke ọgwụ dị iche iche.

3. Ihe mkpuchi

HPMC na-arụ ọrụ dị mkpa na usoro mkpuchi mbadamba. Ike ya dị mma na ihe nkiri na-echebe ọgwụ na-eme ka ọ dị mma ibu:
Mmetụta dị iche iche: Ibe mkpuchi HPMC nwere ike ịdị irè na mbadamba ihe si na mpụga ụwa site na gburugburu ebe obibi iji gbochie ịdị mma, oxiding na photolysis.
Igosipụta dị mma: mkpuchi HPMC nwere ike iwepụta elu mpụta dị larịị, melite ọdịdị na ịdị mfe nke ilo mbadamba.
Redgbanwezi ọgwụ ọgwụ: Site na ntọala HPMC dị iche iche na mkpuchi mkpuchi, na-achịkwa ma ọ bụ ịchekwa a ga-enweta.

4. Ndị nnọchi anya na-edepụta

A na-eji HPMC mee ihe na nkwadebe na-akwado. Site na gel mgbochi ọ dị n'ụdị, ọ nwere ike igbu oge ịtọhapụ ọgwụ ọjọọ ma nweta ọgwụgwọ ogologo oge:
GEL Barchier: na Media Media, HPMC agbasasị ma mee ka gel visos, nke nwere ike ijikwa ọnụego ọgwụgwụ nke ọgwụ.
Enwere ike iji nlezianya na-ahụ maka HPMC nwere ike ịchịkwa nke ọma iji nweta ntọhapụ ọgwụ siri ike na amụma.
Researdment ugboro, a na-edozigharị usoro onunu ogwu nwere ike belata ugboro ole ọgwụ maka ndị ọrịa ma meziwanye nnabata na ịdị irè nke ọgwụgwọ ọgwụ.

5. Nkwadebe mmiri na gels

HPMC na-arụ ọrụ dị mkpa dị ka nke ukwu ma sie ike na mmiri mmiri na-akwado na gels:
Mmetụta dị iche iche: HPMC na-etolite ngwọta colloidal na mmiri, nke nwere ike ime ka viscosis nke ịkwadebe mmiri ma melite nkwụsi ike.
Ndozigharị na-arụ ọrụ: HPMC nwere ike ịnọgide na-enwe viscosis n'ọnọdụ dị iche iche, nke na-enyere aka idozi ọgwụ ọjọọ ma gbochie ọdịda na ụzọ.

6. Ngwa ndị ọzọ

A na-ejikwa HPMC kwadebe nkwadebe Ophthalmic, nkwadebe na-akwado ya na nkwadebe maka ngwa ngwa:
Nkwadebe nke Ophthammalic: A na-eji HPMC mee ihe dị ka igwe na-eto eto na anya mmiri iji belata mgbaàmà anya.
Nkwado nke imi: Dị ka onye na-eto eto na Osimiri Nasal, Hpmc nwere ike ime ka oge mbelata nke ọgwụ na nke imi.
Nkwadebe dị elu: HPMC nwere ike ịpụta ihe nkiri na-echebe na nkwado njikere iji nyere ọgwụ ọjọọ aka ịnọ na anụ ahụ ogologo oge.

Dị ka arụ ọrụ na-arụ ọrụ, hydroxypylthylthylthyl na ụlọ ọrụ ọgwụ. Ọrụ ya n'ọtụtụ arụmọrụ mbadamba, mkpuchi, nkwadebe mmiri na gels na-eme ka mma na-akwadebe ọgwụ ọgwụ. HPMC aghọọla ihe dị mkpa na ihe dị mkpa na ụlọ ọrụ ọgwụ n'ihi oke biocompatibility na akụrụngwa. N'ọdịnihu, na mmepe na-aga n'ihu nke teknụzụ ọgwụ, atụmanya nke HPMC na nyocha ọgwụ ọgwụ na mmepe na imewe na imewe ga-abawanye.