Okwu mmeghe nke HEC na HPMC

HEC (Hydroxyethyl Cellulose) na HPMC (Hydroxyl Methylcellose) Ihe ndị a abụrụla ihe ndị dị mkpa maka akụrụngwa ha pụrụ iche na kemịkal ha.

1. HEC (hydroxyethyth Cellulose)

1.1 Ihe Odide na Njirimara
HEC bụ mmiri na-abụghị nke ionic na-enwetara site na ngbanwe kemịkal nke sellose eke. Ọdịdị ya bụ isi bụ iwebata ndị eji hydroxyethylyythyl na skintose ọkpụkpụ nke cellose. N'ihi hydrophilicy nke hydroxyethyl otu na nhazi ya, hec nwere ezigbo sogrọlity na ihe akụrụngwa na mmiri.

Ihe ngosi HEC na-egosipụta ezigbo adhesion, na-akpụ akpụ na-akpụ akpụ na nke, na acid- na alkali-na-eguzogide ma nwee ezigbo biocompatibility. Ngwongwo ndị a na-eme ka ọ bụrụ oke dị irè, mmachi na ndị na-eme ihe nkiri na sistemụ. Na mgbakwunye, HEC ihe ngwọta nwere ezigbo ThixOtropy, nke nwere ike igosipụta viscosises dị elu n'okpuru obere osisi na-ada ngwa ngwa n'okpuru ike a na-eme ngwa ngwa. Omume a na - eme ka ọ nwee uru ngwa dị mkpa na ọgwụgwọ mmiri dị iche iche.

Usoro nkwadebe 1.2
HEC bụ nke a kwadebere mmeghachi omume nke cellose eke. Commonly used raw materials include cellulose sources such as cotton and wood, which are reacted with ethylene oxide after alkalization to obtain hydroxyethyl cellulose. N'oge mmeghachi omume niile, njikwa nke ọnọdụ mmeghachi omume (dị ka ọnọdụ okpomọkụ, uru na oge) nwere mmetụta dị mkpa na ogo nke ihe nnọchianya, solubality na viscosity nke ngwaahịa ikpeazụ.

Mpempe akwụkwọ 1.3
Ejiri hec mee ihe n'ọtụtụ ụlọ, mkpuchi, kemịkalụ, ọgwụ, ọgwụ na nri. N'ime ụlọ, na-ejikarị ya na ciment na Gypsum dị ka ihe dị irè ma sie ike iji mee ka arụ ọrụ ya na akụrụngwa mgbochi. Na ụlọ ọrụ mkpuchi mkpuchi ahụ, enwere ike iji hec dị ka nke ukwu na rhiology medifier maka mkpuchi mkpuchi mmiri iji melite adhesion na ịdị larịị nke mkpuchi. Na kemịkal kwa ụbọchị dị ka ncha ntutu na aka aka, HEC dị ka onye na-eto eto na moisliurza inye ngwaahịa ahụ ezigbo mmetụta na nkwụsi ike. Na mgbakwunye, na ụlọ ọrụ ọgwụ na ngwaahịa ọgwụ, HEC dị ka ihe mkpuchi maka mbadamba, na ndị na-emebu ya na capsules, na ndị na-emekwa ka nri dị mma na oke mma.

2.

2.1 Ọdịdị na Njirimara
HPMC bụ nke na-abụghị nke Iic cellulose ether site na iwebata hydropyyyl na methoxy otu n'ime akwara sellose. Yiri HEC, HPMC nwere ezigbo mmiri solbility, ndị na-akpụ akpụ, ihe nkiri na-akpụzi akụrụngwa na bayolomatibility. N'ihi otu methoxy na hydroxypyl na nhazi ya, HPMC ọ bụghị naanị na-enwe ezigbo solibality na mmiri, kamakwa na-egosipụta ike ọrụ dị elu na Njirimara Njirimara.

Vieocosity nke HPMC Ngwọta na-emetụta oke okpomọkụ. N'ime ụfọdụ ọnọdụ okpomọkụ, viscosity hpmc ngwọta na-agbadata na oke okpomọkụ. Na mgbakwunye, HPMC nwekwara ezigbo GEL Njirimara. Mgbe ihe okpomoku okpomoku gafere, a ga-etolite gel. Ngwongwo a nwere uru ngwa puru iche na nri na ogwu.

Usoro nkwadebe 2.2
Nkwadebe nke HPMC yiri HPT, ma ebukwa ya site na mmeghachi omume nke celluse. Ọtụtụ mgbe, cellulose na-emegharị ya na propylene oxide na methyl chloride n'okpuru ọnọdụ alkaline iji webata otu na metoxy. Njirimara nke hpmc (dika vibut na okpomoku Gel) site na imeghari ogo nke nbanye na ọnọdụ mmeghachi omume.

2.3 Ubi Akwukwo
HPMC nwere ọtụtụ ngwa dị iche iche n'ọhịa, ọgwụ, nri na kemịkalụ kwa ụbọchị. N'ime ụlọ, a na-eji HPMC mee ihe n'ọtụtụ ngwaahịa ciment dị ka Typsum ngwaahịa, mmiri na-eji ike na ihe mkpuchi iji melite arụmọrụ na ịdị ndụ nke ihe ahụ. N'ọnwa ọgwụ, a na-eji HPMC mee ihe dị ka onye na - achịkwa ya, ihe nrapado na capsole mkpuchi ihe maka mbadamba, nke nwere ike ijikwa ọgwụ ọjọọ ma melite nkwụsi ike nke ọgwụ. Na ụlọ ọrụ nri, a na-eji HPMC mee ihe dị ka nke na-eme ihe dị ka nke a na-eme na ngwongwo, ngwaahịa mmiri ara ehi na contiments iji meziwanye udiri na uto nke ngwaahịa. Na mgbakwunye, a na-ejikwa HPMC na-ejikarị ọgwụ ndị dị ka ncha ntutu kwa ụbọchị dị ka ncha ntutu, ọfụma, nke dị ọcha, wdg, na-enye ngwaahịa dị mma.

Dị ka abụọ dị mkpa cellose derivatives, hec na hpmc na-arụ ọrụ dị mkpa n'ọtụtụ ụlọ ọrụ. A na-eji HEC mee ihe eji arụ ọrụ, kemịkal na ọgwụ kwa ụbọchị na ọgwụ n'ihi oke na-eto eto, na-akpụ akpụ na-akpụ akpụ na biocompatisibility. N'aka nke ọzọ, n'aka nke ọzọ, na-arụ ọrụ dị mkpa na owuwu ahụ, ọgwụ na ụlọ ọrụ nri n'ihi ihe akụrụngwa ya pụrụ iche na mpaghara ngwa ngwa ya. Site na oganihu nke teknụzụ, usoro nkwadebe na mpaghara ntinye akwụkwọ abụọ a ga-aga n'ihu ịgbasa, na-ewetara ndị ọzọ ohere maka mmepe nke ọrụ ndị metụtara.