Hydroxypyl Methylcellose (hpmc) bụ polymer na-agbanye mmiri na ụlọ ọrụ, ọgwụ na nri. Otu n'ime ọrụ ukwu nke HPMC na ngwaahịa dị iche iche bụ iji dozie viscosity, nke a na-enweta site na usoro ya na mmekọrịta ya na sonvents (ọ na-abụkarị mmiri).
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HPMC nwere ndị mejupụtara bakilose ballone na methoxy na hydroxypyl. A ga-ebu ụdị cellulose ya na-ebu ọnụ ọgụgụ dị ukwuu nke otu hydroxy, nke nwere ike ijikọ sods na ụmụ irighiri mmiri, si otú ahụ mee ka vioges mmiri nke ihe ngwọta. Ndị uwe ojii hydroxypypyl na methoxy na-emetụtakwa ime ya na mmiri. Na mmiri, yinye Hpmc molecular nwere ike imeghe ma na-etinye oke mmiri, si otú ahụ na-abawanye vicosict nke ihe ngwọta.
Ofdị HPMC dị iche iche ga-egosi njirimara dị iche iche n'ihi ogo ha dị iche iche na Methoxy na Hydroxypyl nbanye. N'ikwu ya n'ozuzu, HPMC na ogo dị elu nke nnọchi anya Hydropyy nwere ike ịbawanye ụba viscositty ike, ebe HPMC nwere nnukwu ọdịnaya methoxy dị iche iche dị iche iche na ndagwurugwu. Ya mere, usoro ụmụ ahụhụ nke HPMC nwere mmetụta dị mma na mmetụta ọ na-abawanye vicsose ya.
2. Nkwenye njiri mara na viscosis nke HPMC
HPMC nwere ezigbo mmiri solublity, nke na-enyere ya aka ịbawanye viccosictons. Na mmiri, agbụ molecular nke mmiri HPMC na-enweta mmiri ma na-etolite ihe owuwu network, nke na-ebute mbelata mmiri nke ihe ngwọta ahụ na mmụba na viscosise. Usoro a bụ usoro nzọụkwụ, yana okpomọkụ na pH nwere mmetụta dị ukwuu na ya. N'ozuzu, hpmc na-agbasa ngwa ngwa na obere okpomọkụ, mana visce ya na-abawanye na oke okpomọkụ. Ya mere, elu na-efe efe na mpaghara ụfọdụ, ka ukwuu viscosity nke ihe ngwọta.
Nkwekorita nke HPMC na-akowa na uru ph nke onye na-ajụ ase. Na nnọpụiche ndị na-adịghị ike alkaline, HPMC swills ka mma ma na-abawanye visity; Ọ bụ ezie na ọnọdụ actic siri ike ma ọ bụ alkaline, solublity na viscosity nke HPMC na-egbochi. Ya mere, na ngwaahịa dị iche iche, ikike viscits ike nke HPMC dịkwa mkpa ịtụle uru pị uru nke ọkara ahụ.
3. Mmetụta nke HPMC uche na viscosis
Nta nke HPMC bụ otu n'ime ihe ndị dị mkpa na-emetụta viscosity. Dị ka ngwọta nke HPMC na-abawanye, netwọkụ molecular guzobere na ngwọta ghọrọ mkpụrụ na viscosity na-abawanye nke ukwuu. Na ala dị ala, mmekọrịta dị n'etiti agbụ Hpmc adịghị ike, na viscosis nke ihe ngwọta anaghị agbanwe ọtụtụ. Agbanyeghị, mgbe HPMC itinye aka na ọkwa ụfọdụ, njigide na ntinye n'etiti eriri moleculation ga-eme ka viocty dị ukwuu.
Nnwale na-egosi na mgbe ịta HPMC bụ n'ime otu ebe, ọhụụ ya na-abawanye n'ụzọ na-abawanye na itinye uche. Agbanyeghị, mgbe ịta ahụhụ dị oke elu, Njirimara Njirimara nke ihe ngwọta ga-agbanwe, na-egosi pseudoplastity ma ọ bụ Thixtyropy, na vixothrose, na mmụba nke ọnụego ya. Ya mere, na ngwa bara uru, ọ dị mkpa ka na-achịkwa ezi uche dị ka mkpa ụfọdụ iji nweta ụdị vishosis.
4. Mmetụta nke oke molecular na viscosity
Ibu molecular nke Hpmc bụkwa ihe dị mkpa na-ekpebi viscosity ya. N'ozuzu, ibu molecular arọ nke hpmc, onye dị elu viscosity nke ihe ngwọta ya. Nke a bụ n'ihi na hpmc na nnukwu mowocular ibu nwere ike ịpụta abụ dị ogologo na ntọala netwọ dị mgbagwoju anya, na-egbochi mmiri nke ihe ngwọta ma na-amụba viscosise. Ya mere, enwere ike iji ya dị iche iche molecular dị iche iche iji dozie viscositse ngwaahịa dị iche iche.
Na ụfọdụ ngwa, ịhọrọ nnukwu ihe eji eme ihe dị elu molecular nwere ike ime ka ihe dị iche na nke ngwaahịa a, dị ka ihe na-ewu ewu na ụlọ; Mgbe ha nọ na ngwa ndị ọzọ, dị ka ubi ọgwụ, HPMC dị ala iji dozie ọnụego ọgwụ ma ọ bụ melite uto.
5. Mmetụta nke okpomọkụ na viscosity nke HPMC Ngwọta
Viscosity nke HPMC gbanwere nke ọma na ọnọdụ okpomọkụ. N'ikwu okwu n'ozuzu, viscosity HPMC n 'mbelata okpomọkụ dị elu. Nke a bụ n'ihi na okpomọkụ dị elu na-emebi njikọ hydrogen n'etiti ụmụ irighiri hpmc ma belata ogo nke bata na-apụ apụ apụ, si na -ebelata viscoside nke ihe ngwọta. Agbanyeghị, n'ọtụtụ ọnọdụ pụrụ iche, viscosity HPMC nwere ike ịbawanye n'ime ụfọdụ ọnọdụ okpomọkụ, nke jikọtara ya na usoro ihe owuwu ya na gburugburu ya.
Na oge dị ala, viscosity HPMC Ngwọta dị elu na mmegharị nke eriri mmiri. Ngwongwo a na - eme ka ọ rụọ ọrụ nke ọma na ngwa ebe viser nke ngwaahịa na obere okpomọkụ kwesịrị ịmụba.
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Ngwọta HPMC na-egosipụtakarị njiri mara nke, ya bụ, vissese na-ebelata na ịba ụba nke ya. Na ala dị ala, owuwu netwọdi nke hpmc moleculatilati nke zuru ezu, nke na-egbochi mmiri nke ihe ngwọta ahụ, si otú a na-egosipụta viocosity dị elu. Agbanyeghị, na oke ọnụego Shear, a na-abanye na njedebe na njikọta nke eriri elolalọ, ma viscese na-ebelata. A na-ejikarị ụlọ a na ụlọ ọrụ dị ka ihe na-ewu ụlọ, ihe osise na mkpuchi, ma melite ọrụ nke ngwaahịa n'oge owuwu.
7. Mmetụta nke ihe mgbakwunye mpụga
N'ọtụtụ ngwa, a na-ejikarị HPMC na-ejikarị ya na ihe ndị ọzọ. Dị iche iche nke ihe mgbakwunye dị iche iche, dị ka nnu, surfactants na polymers ndị ọzọ, ga-emetụtakwa viocosit nke HPMC. Dịka ọmụmaatụ, ụfọdụ mgbakwunye nnu nwere ike belata viscosity nke HPMC Ngwọta na-egbochi mmekọrịta dị n'etiti HPMC molecular a kpụrụ network. Somefọdụ ndị dị iche iche nwere ike ịrụ ọrụ sonergistly na HPMC iji bulie ọhụụ ọhụụ nke ihe ngwọta.
Dị ka ndị na-eji na-eji Trodiner, mmetụta HPMC na viscosity viscosity bụ ihe na-akpata usoro ihe owuwu ya, njiri mara mma, na-ada na mgbakwunye na ihe mgbakwunye. Site na ezi uche na-edozi parameters ndị a nke HPMC, enwere ike nweta njikwa ngwaahịa ngwaahịa dị iche iche iji gboo mkpa nke ngwa ngwa dị iche iche.
Oge post: Feb-17-2025