Hydroxypyl Methylcelllose (HPMC) bụ mmiri na-ejikarị cellusate na-eji ọtụtụ ebe niile na-akwụsị akwụsị. Nkwụsi ike nke nkwụsị na-ezo aka ike nke ihe ndị siri ike ka ọ ghara ịdị na-akpọsa ya na mmiri mmiri ogologo oge na-enweghị nkọcha. Njirimara anụ ahụ na kemịkal nke hpmc na-eme ka ọ rụọ ọrụ dị mkpa n'ịzigharị nkwụsi ike.
Njirimara nke HPMC
Akụrụngwa na kemịkal
HPMC bụ ihe na-atọ ụtọ site na elekere na hydroxypypration nke celluse. Ọdịmma ya nwere hydrophylylylylyyylylylyyylylyyylylyylylythythythythyth (-Oh) na hydroxyl ìgwè dị iche iche, nke na-eme ya mmiri-na-agbanye na elu. HPMC nwere ike ịmalite ngwọta visos na mmiri, yana mgbanwe ya gbanwere na ịta, ọnọdụ na pH.
Njirimara viscosis
Ngwọta nke HPMC na-egosipụta ihe ndị na-abụghị ndị Newtontian, visce ya na-abụghị ndị Newtontian, na-agbadata na ịba ụba nke mmiri, ya bụ, ọ na-egosipụta akụrụngwa na-acha uhie uhie. Ngwongwo a nwere mmetụta dị mkpa na akparamagwa ahụ n'ihi na ọ nwere ike iwepụta viscosity na - egbochi ndagide nke ụmụ irighiri ihe mgbe ị na - akpali ma ọ bụ na - enye ya.
Usoro nke mmetụta nke HPMC na nkwụsi ike nke nkwụsị
1. Mmetụta dị omimi
Mmetụta ndị na-emekarị nke Hpmc bụ igbochi nkụnye aka nke ụmụ irighiri ihe site na ịba ụba viscosity nke nkwusioru ahụ. A na-egosiputa mmetụta ndị dị omimi na akụkụ ndị a:
Ikwusa viscosity nke ọkara ahụ: HPMC nwere ike iwelie viscosity nke nkwusioru ahụ, si otú a belata ọnụego nke na-ada ada na mmiri mmiri. Nke a bụ n'ihi na dịka Iwu Stokes si kwuo, ọnụego ndọtọ bụ ihe na-emetụtaghị viscosity nke ọkara ahụ. Mmụba na viscosity nwere ike iwepu nsị nke irighiri ihe ma mee ka nkwụsi ike nke nkwusioru ahụ.
Na-etolite ihe owuwu netwọkụ atọ: HPMC nwere ike ịmalite ụlọ ọrụ netwọọk dị ka mmiri, nke nwere ike ijide ma dozie ihe ndị siri ike ma gbochie ha idozi. A na-ejikọ ihe owuwu netwọkụ a site na njikọta hydrogen na mmekọrịta hydrophobic, na-eme ka ụmụ irighiri ihe ndị a chụsasịrị.
2.. Mmetụta Electrostatic
Ihe owuwu nke HPMC na-eburu ya ụgwọ (dịka, site na hydroxyl ma ọ bụ ìgwè dị iche iche), nke nwere ike ịmekọrịta na ụgwọ elu nke ihe siri ike na nkwusioru. Site na idozi ike dị elu nke irighiri ihe, HPMC nwere ike ịbawanye ihe mkpuchi electrostatic dị n'etiti irighiri ihe, si otú ahụ gbochie nchịkọta na flocculations.
Activerụ ọrụ: Nleta HPMC nwere ike ịgbanwe ụgwọ ụgwọ dị elu, na-abawanye mmegharị electrostatic n'etiti irighiri ihe, ma belata ọchịchọ nke irighiri ihe.
Idozi sistemụ colloidal: Na ụfọdụ sistemụ colloidal, HPMC nwere ike inye aka belata ngwakọta colloidal ma gbochie ha ịchịkọta ndị agha ma ọ bụ ike ndị ọzọ mara mma.
3. Mmetụta ihe mgbochi ihe mgbochi
HPMC Molecules nwere ike itolite ọnya na-egbochi ya na nkwusioru, nke nwere ike igbochi kọntaktị na nchịkọta n'etiti irighiri ihe, site na ịbawanye nkwụsi ike nke nkwusioru.
Spatiers mgbochi: ụmụ irighiri akwara na-etolite akwa akwa na-arị elu, nke nwere ike igbochi ụmụ irighiri ihe site na ya, si otú a belata ohere nke nchịkọta na idination.
A na - akwụsị nkwụsi ike:
4.
Arụ ọrụ dị elu nke HPMC na-enye ya ohere ịgbaso ya na elu nke ihe siri ike iji mepụta mkpuchi mkpuchi. Ikike a abụghị naanị n 'elu irighiri ihe, kamakwa na-eme ka ha dị mfe ịgbasa na mmiri mgbasa ozi.
Mgbanwe elu elu: Site na mgbasa ozi n'elu nke irighiri ihe, Hpmc nwere ike ịgbanwe akụrụngwa anụ ahụ na kemịkalụ nke urughuru ma na-abawanye nzụlite na nkwụsi ike nke ihe.
Belata nsogbu nsogbu: Ọrụ dị elu nke HPMC nwere ike belata nsogbu nke mmiri na elu ala, na-eme ka ọ dịkwuo mfe iji gbasaa na ọkara.
Ihe atụ nke ngwa HPMC na nkwụsị dị iche iche
Nnyocha omume ọgwụ
Na nkwụsị ọgwụ, a na-ejikarị HPMC na-eji edozi ọnọdụ mgbasa ozi na-arụ ọrụ ọgwụ. Site na idozi uche na oke nke hpmc, ihe ndị na - eme nsị nke nkwụsị ahụ na - ekesa ya n'oge nchekwa na iji, na - ejide agbanwe agbanwe.
Na enyo enyo nke ọgwụ nje ma ọ bụ ọgwụ nje, a na-eji HPMC mee ihe dị ka onye na - egbochi ịgbanye ọgwụ mgbe ị na - enye ọmịiko.
Nnọọ nkwụsị na-egbu egbu
Na igbu nkwụsị, HPMC nwere ike imeziwanye ọgwụ na-egbu egbu na mmiri ma belata nkwenye nke ọgwụ na-egbu egbu, si otú a na-eme ka arụmọrụ na arụmọrụ nke pesti.
Na ahụhụ ma ọ bụ na-egbu egbu ma ọ bụ HPMC nkwụsi ike, enwere ike iji HPMC mee ihe dị ka onye a na-achụsasị na Peadrener iji hụ na enwere ike kesaa ihe ndị na-ata ahụhụ na-ekesakarị ọgwụ na-arụ ọrụ ma melite nsonaazụ nchebe.
Nri na ihe ịchọ mma
Na nri na ụlọ ọrụ ịchọ mma, a na-ejikarị HPMC mee ihe dị ka mma na Truener. Iji maa atụ, na ngwaahịa dị ka emulsions ma ọ bụ ude, HPMC nwere ike melite udidi nke ngwaahịa ahụ ma gbochie stratification na ọdịda.
Na ude anụ ahụ, enwere ike iji hpmc dị ka nke ukwu iji nye mmetụta dị mma ma kwalite ihe emulsification, kesaa ihe e ji arụ ọrụ, na nkwụsi ike nke ngwaahịa ahụ ka mma.
HPMC na-emetụta nkwụsi ike site na usoro dị iche iche, gụnyere ịbawanye viscosity, na-eme ka ihe mgbochi okwute na elu ọrụ. Usoro ndị a na-arụkọ ọrụ iji mee HPMC ihe dị mma iji mee ka nkwụsi ike nke nkwụghachi ụgwọ. Ngwa ya dị na ubi ọgwụ, ọgwụ na-egbu egbu, nri na ihe ịchọ mma na-akwado oke uru ya dị ka eriri nkwụchi. N'ọdịnihu, dị ka ihe achọrọ maka ngwa nkwusioru na-aga n'ihu ka mmụba, nyocha na itinye HPMC ga-aga n'ihu na-eme ihe.
Oge post: Feb-17-2025