HPMC hydrophilic ma ọ bụ lipophilic?

Hydroxypyl Methylcellose (HPMC) bụ pocymer na-ejikarị ngwa na-eji ọgwụ na ọgwụ, nri, ihe ịchọ mma na owuwu. Ajụjụ nke hydrophilicity na lipophility nke hpmc kacha dabere na ihe owuwu kemịkal na molecular.

Ọdịmma na Njirimara nke HPMC
HPMC bụ ihe na-abụghị nke ionic cellulose mejupụtara site na iwebata hydropyyl na methyl n'ime ihe owuwu cellular. Ahịhịa akwara ya nwere hydrophylyl (-Oh) na lipophilic methyl (chch3) na hydroxyl (-ch) Chọọ. Ya mere, o nwere njikọ abụọ, ma hydrophilic na lipophilic, mana hydrophilicy dịtụ mma. Ngwongwo a na - enye ya ezigbo solubity, na - akpụ ihe nkiri na ihe ndị na - eto eto, ma nwee ike ijikọ mgbasa ozi calloidal na solutions ngwọta.

Hydrophicality hpmc
N'ihi ọnụ ọgụgụ buru ibu nke ìgwè hydroxy na HPMC, yinye ya nwere hydrophilicy siri ike. Na mmiri, HPMC nwere ike ịpụta agbụ hydrogen, na-ekwe ka ụmụ irigbu jupụta na mmiri ma na-etolite ngwọta dị elu. Na mgbakwunye, HPMC nwekwara njigide mmiri dị ukwuu ma na-ejikarị ya dị ka nke na-agbaze ma kwụsie ike na ọgwụ, nri na ịchọ mma. Iji maa atụ, enwere ike iji HPMC mee ihe dị ka onye nnọchi ọgwụ na-akwado ọgwụ na-akwado ọgwụ iji gbuo oge ịtọ ọgwụ na ahụ ma melite nkwụsi ike nke nrụpụta ọgwụ.

Lipophilicy nke hpmc
Methyl na ìgwè hydroxypyl na HPMC Molekule nwere ụfọdụ hydrophobity, ọkachasị na oke ikuku ma ọ bụ ihe mgbaze ndị na-eme ka ọ bụrụ ihe mgbakwụnye nkịtị iji mepụta ihe ngwọta siri ike. Lipophilicity ya na - enyere ya aka ịgwakọta ihe ndị na - eme mmanụ mmanụ, nke na - eme ka ngwa nke hpmc na mmiri na mmiri (o / w) emulsions na ebubreyo. N'ime ụfọdụ emulsions ma ọ bụ nkwadebe nke hpmc na-enyere aka iji usoro a na-ekesasịsị na-esite na ya na ihe hydrophobic, na-ejikwa nkesa na nkwụsi ike nke ihe ndị a na-eme.

Ngwa nke HPMC
Nkwadebe ọgwụ: A na-ejikarị Hụ ọgwụ na mbadamba na mbadamba na mbadamba ya, na-eji hydrophilishy na Njirimara na-akpụzi ihe nkiri iji chịkwaa ọgwụ mwepụta ọgwụ.
Industrylọ ọrụ nri: N'ime nri, a na-eji HPMC mee ihe dị ka nke ukwu na mmiri na-agbatịkwu ndụ ndụ nri ma melite uto.
Ihe eji eme ihe: mmiri hpmc's sọsọ na mmetụta na-eme ka ọ bụrụ ihe owuwu ciment na owuwu, na-eme ka ọrụ na mmiri na-enwe ike nke ihe ahụ.
Enwere ike iji ihe ịchọ mma: na ngwaahịa nlekọta anụ ahụ, enwere ike iji HPMC dị ka eriri mgbochi. N'ihi hydrophilicity ya, ọ nwere ike itolite matrix iji nọgide na-enwe mmetụta moistiring na udidi nke ngwaahịa a.
HPMC bụ ihe polymer polymeric nke bụ ma hydrophilic na lipophilic, mana n'ihi na ọ nwere ọtụtụ hydroxy dị iche iche, ọ na-egosipụta ike hydrophilicity.