Hydroxypyl Methylcelllose (Hpmc) bụ pocymer polymetic na-ejikarị ọgwụ, nri, owuwu, ihe owuwu, ihe ịchọ mma na ubi ndị ọzọ. Ọ nwere ezigbo mmiri, akụrụngwa colloidal na nkwụsi ike, yabụ, ọ nwere ngwa dị mkpa na ụlọ ọrụ dị iche iche. Iji hụ na ọ dị mma na ịdị ọcha ya, ọ dị mkpa njirimara kwesịrị ekwesị. Ihe ndị a bụ ọtụtụ njirimara njirimara njirimara maka hydroxylthylthylthyl, na-ekpuchi akụkụ dịka ọdịdị, solkality dị iche iche na kemịkalụ kemịkalụ.
1. Nlele ahụ
HPMC na-acha ọcha na ntụ ntụ na-acha ọcha ma ọ bụ ihe na - enweghị isi. Site n'ikiri ọdịdị ya, ị nwere ike ikpe ọmụma ma ọ bụ hpmc dị ọcha. Mgbanwe agba ọ bụla ma ọ bụ ọnụnọ nke adịghị ike ma ọ bụ ọnụnọ nwere ike igosi na ihe atụ ahụ adịghị ọcha ma ọ bụ mmetọ.
2. Nchọpụta solubality
HPMC nwere ezigbo sọsọ, karịsịa na mmiri. Tinye obere ego nke ihe nlele ahụ n'ime mmiri ma bido nwayọ. Ọ bụrụ na ọ nwere ike igbari ngwa ngwa ma na-etolite colloidal ngwọta, ọ pụtara na ihe atụ ahụ bụ hydroxypylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthylthyl Ọsọ ọsọ na viscosity nke ihe ngwọta nwere ike ịbụ ogo nke Hpmc na ọdịnaya nke hydropyyl na Methyl Chemicals.
N'otu oge ahụ, ike ịdọ aka na hpmc na sosganic solvents dị ka ọkọlọtọ njirimara. HPMC na-agbanye na ọtụtụ sontù sorvents (dịka acketone, ethanol, wdg), mana enweghị mgbochi na mgbatị ahụ. Enwere ike ikwenye agwa a site na nnwale na-anwale ya na nkwado kwesịrị ekwesị.
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Openroscopy (IR) bụ ngwa njirimara ziri ezi nke nwere ike inye aka gosipụta usoro nke HPMC. Akụkụ bụ isi nke HPMC bụ ihe dị ka Methyl (-CH3) na hydroxyl (-ch2CH (oh) Ch3). Enwere ike ikwenye ọnụnọ ndị otu a site na ọnụ ọgụgụ dị iche iche nke Igwe Spimem.
Ọnụ ọgụgụ dị iche iche nke HPMC's IRR Thurum nke HPMC gụnyere:
2920 cm-1 (Chang na-agbatị oke)
1450 cm-1 (ch na-agbagharị oke)
1100-1200 cm-1 (agba agba agba)
3400 cm-1 (Oh na-agbatị na-ama jijiji, ọnụ ọgụgụ kachasị elu nwere ike gbanwee n'ihi ọnụnọ mmiri)
Site na iji ihe nlere nke IR nke Accram, enwere ike iji ya tụnyere ụdị ihe nlele a na-amaghị iji gosipụta njirimara nke ihe nlele ahụ.
4. Ihe ngosi kemịkalụ
HPMC, dị ka onyinye ether, nwere ụfọdụ ihe mmeghachi omume kemịkalụ ma enwere ike ịchọpụta site na mmeghachi omume kemịkal dị mfe.
(1) Mmeghachi omume n'okpuru ọnọdụ acidic:
Gbanyụọ obere obere mmiri, gbakwunye nwayọ hydrochloric acid, na okpomọkụ. Ọ bụrụ na ihe akụrụngwa na-egosi na ngwọta ahụ, ọ pụtara na o nwere HPMC. Enwere ike ịmata mmeghachi omume a site na nkwụsi ike nke hydropyyl nathyl n'okpuru ọnọdụ acidic.
(2) Mmeghachi omume n'okpuru ọnọdụ alkaline: HPMC sọpụrụ na mmiri iji mepụta ngwọta colloidal. Ọ dịghị mfe ịgbari n'okpuru ọnọdụ alkaline (dịka sodium hydroxide ihe ngwọta), nke metụtara hydrophilicity na Njirimara Hdrogel. Ọ bụrụ ngwọta ya bụ turbid ma ọ bụ buo amụma, ọ pụtara na HPMC dị ugbu a.
5. Njirimara nke usoro viscy HPMC bu ihe eji eme ihe omuma, ya mere enwere ike mata ya site na viscosis ya na vissisis ya. N'ikwu ya n'ozuzu, HPMC ga-etolite ihe dị iche iche nwere ụfọdụ viodity mgbe ị gbasịrị na mmiri, na viscosity na-abawanye ụba nke ogo ya.
Iji tụọ viscosity, ihe ngwọta nke HPMC Ngwọta site na iji Vuitentanet Vuivat Vuiver ma ọ bụ vie tube iko. Dabere na ịdị arọ molecular nke Hpmc na ntinye uche nke ihe ngwọta, enwere ike ịkọwa viscosity ya. Ọ bụrụ na viscosity nke ihe nlele ahụ dị ala karịa nke ọkọlọtọ HPMC Ngwọta, ọ nwere ike igosipụta na ihe ndị ọ na-adịghị ọcha ma ọ bụ oke molecular dị ala.
6 Mgbe HPMC kpụ ọkụ n'ọnụ, enwere ike ịhụ mgbanwe ya n'oge okpomọkụ dị iche iche. Na-ekwu okwu, HPMC ga-amalite decom na 180-200 ℃, na-ahapụ ụfọdụ ihe na-agbanwe agbanwe (dịka mmiri na sosversic). Mgbanwe na isi okwu nwere ike ikwenye n'ihu ma ihe atụ ahụ dị ọcha hpmc.
7. Ngwọta na usoro nchekwa
Ngwọta a guzobere mgbe HPMC sọfọrọ n'ozuzu nwere oke esemokwu dị ala. Ọnọdụ esemokwu nke HPMC Ngwọta nwere ike tụọ site na iji tensiomeomes ma ọ bụ ụzọ aghụghọ. Ọ bụrụ na ọ dakọtara elu nke ọkọlọtọ nke ọkọlọtọ, ọ pụtara na ihe atụ ahụ bụ HPMC.
Ihe ndị a dị n'elu na-ewepụta ọtụtụ usoro dị mfe na nke dị mfe iji chọpụta hydropyylthylthylthyl methylcelllose (hpmc). Thezọ ndị a na-achọpụta HPMC site na ọtụtụ akụkụ dịka ọdịdị, ịghazigharị, mmegharị ahụ, na-egosi maka itinye ya n'ọrụ na ụlọ ọrụ dị iche iche.
Oge post: Feb-19-2025