Ka anyị kwuo maka hydroxypropyl methyl cellulose HPMC na otu esi atụ viscosity ya.Viscosity ebe a na-ezo aka na viscosity pụtara ìhè, nke bụ ihe dị mkpa na-ezo aka na hydroxypropyl methyl cellulose.
Ọkọlọtọ.Ụzọ nha a na-emebu bụ nha viscosity rotational, elele viscosity capillary na nha viscosity ọdịda ọdịda.Usoro mkpebi nke hydroxypropyl methyl cellulose bụ adhesion capillary.
Usoro nke ikpebi ogo, na-eji Uchs viscometer.Na-emekarị mkpebi nke ngwọta bụ 2% mmiri mmiri ngwọta, usoro bụ: V=Kdt.V bụ viscosity na mpa.s na K bụ viscometer mgbe niile.
D bụ njupụta na okpomọkụ mgbe niile na T bụ oge site n'elu ruo na ala site na viscometer na sekọnd.Ụzọ ọrụ a na-akawanye njọ, ma ọ bụrụ na e nwere ihe na-adịghị edozi.
Okwu dị mfe ịkpata njehie, ọ na-esiri ike ịchọpụta àgwà hydroxypropyl methyl cellulose.Ugbu a, a na-ejikarị elele viscosity nke viscometer rotary, nke a na-ejikarị eme ihe na China.
Usoro nke viscometer NDJ-1 bụ η=KA.η bụ viscosity, dịkwa na mpa.s, K bụ ọnụọgụ nke viscometer, na α bụ ọgụgụ nke ihe nrịbama viscometer.
Hydroxypropyl methyl cellulose 2% usoro ule viscosity:
1, usoro a kwesịrị ekwesị maka mkpebi siri ike nke viscosity na-adịghị na Newtonian (ihe ngwọta polymer, nkwusioru, emulsion dispersion liquid ma ọ bụ ngwọta surfactant, wdg).
2. Ngwa na ngwa ngwa
2.1 Viscometer Rotary (NdJ-1 na NDJ-4 bụ ndị China Pharmacopoeia chọrọ)
2.2 mmiri mmiri na-ekpo ọkụ mgbe niile na-ekpo ọkụ mgbe niile 0.10C
2.3 Ogo akara okpomọkụ bụ 0.20C, nke a na-enyocha kwa oge.
2.4 Viscometers mita ugboro ugboro na-eji usoro nkwụsi ike ugboro ugboro (dị ka NDJ-1 na NDJ-4) ga-edobe.Nzizi nke 1%.A
8. Og sample tụrụ n'ụzọ ziri ezi na-etinye n'ime a akọrọ, toned 400mL ogologo beaker.Tinye ihe dị ka 100mL nke mmiri ọkụ 80-90 degrees ma mee ka 10min kewapụ
Kwusachaa, kpalie ma gbakwunye mmiri oyi na 400ml na mkpokọta.Ka ọ dị ugbu a, kpalie na-aga n'ihu maka 30min iji mee ngwọta 2% (W / W), ma tinye ya na friji maka ịsa ahụ ice ka ọ dị jụụ ruo mgbe ọ na-etolite ice dị n'elu.
Wepụ ma tinye n'ime tankị okpomọkụ mgbe niile iji mee ka okpomọkụ dị n'etiti 20 ℃ 0.1 ℃.
3.1 A ga-eme nrụnye na ịrụ ọrụ nke ngwá ọrụ dịka ntuziaka ọrụ nke ngwá ọrụ ahụ si dị, a ga-ahọrọ rotor na rotor kwesịrị ekwesị dị ka viscosity nso nke ngwaahịa a nwalere na ndokwa nke pharmacopoeia n'okpuru ederede nke ngwaahịa
Ọsọ ntụgharị.
3.2 Gbanwee okpomọkụ mmiri na-ekpo ọkụ mgbe niile dị ka mkpebi siri ike n'okpuru ihe ọgwụ ọ bụla.
3.3 A na-etinye ngwaahịa ule ahụ n'ime akpa ahụ akọwapụtara na ngwa ahụ, a na-atụkwa akụkụ ntụgharị (a) dịka iwu si dị ka nkeji 30 nke okpomọkụ na-adịgide adịgide.Gbanyụọ moto ma malitegharịa ya maka mkpebi siri ike ọzọ
Ọdịiche dị n'etiti ụkpụrụ pụtara ekwesịghị gafere 3%, ma ọ bụghị ya, ekwesịrị ịme nha nke atọ.
3.4 Gbakọọ uru ule abụọ a dị ka usoro iji nweta viscosity siri ike nke ngwaahịa a nwalere.
4. Dekọọ ma gbakọọ
4.1 Dekọọ ụdị viscometer rotary, nọmba rotor na ọsọ ejiri, viscometer na-adịgide adịgide (Uru K 'uru), okpomọkụ tụrụ na nha ọ bụla.Uru.
Usoro ịgbakọ nke 4.2
Dynamic viscosity (MPa”s) = Ka ebe K bụ viscometer na-atụ mgbe niile na mmiri ọkọlọtọ ama ama na A bụ akụkụ ntụgharị.
Oge nzipu: Mee-18-2022