Hydroxypropyl methylcelluloseHPMC) bụ ihe na-abụghị ionic, cellulose mmiri na-agbakọta ether.Ọdịdị na-acha ọcha ruo ntakịrị ntụ ntụ ma ọ bụ ihe granular, enweghị ụtọ, enweghị isi, adịghị egbu egbu, nke siri ike nke kemịkalụ, wee gbazee n'ime mmiri iji mepụta ngwọta dị nro, nke doro anya na viscous.Otu n'ime ihe kachasị mkpa nke hydroxypropyl methylcellulose na ngwa bụ na ọ na-abawanye viscosity nke mmiri mmiri.Mmetụta siri ike na-adabere na ogo polymerization (DP) nke ngwaahịa ahụ, ntinye nke cellulose ether na ngwọta mmiri, ọnụ ọgụgụ nke shear, na okpomọkụ ngwọta.Na ihe ndị ọzọ.
01
Ụdị mmiri mmiri nke HPMC aqueous ngwọta
N'ozuzu, enwere ike igosipụta nrụgide nke mmiri na-agbapụta mmiri dị ka ọrụ nke naanị ọnụ ọgụgụ shear ƒ (γ), ma ọ bụrụhaala na ọ bụghị oge.Dabere n'ụdị ƒ(γ), mmiri nwere ike kewaa n'ụdị dị iche iche, ya bụ: mmiri mmiri Newtonian, mmiri dilatant, mmiri mmiri pseudoplastic na mmiri rọba Bingham.
E kewara cellulose ethers ụzọ abụọ: otu bụ cellulose ether na-abụghị ionic na nke ọzọ bụ ionic cellulose ether.Maka rheology nke ụdị abụọ a nke cellulose ethers.SC Naik et al.duziri ọmụmụ ihe ntule zuru oke na nke usoro na hydroxyethyl cellulose na sodium carboxymethyl cellulose ngwọta.Nsonaazụ gosiri na ma ndị na-abụghị ionic cellulose ether ngwọta na ionic cellulose ether ngwọta bụ pseudoplastic.Mmiri na-asọ asọ, ntụgharị nke na-abụghị Newtonian, na-abịarute mmiri mmiri Newtonian naanị na oke dị ala.Pseudoplasticity nke hydroxypropyl methylcellulose ngwọta na-arụ ọrụ dị mkpa na ngwa.Dịka ọmụmaatụ, mgbe a na-etinye ya na mkpuchi, n'ihi njiri mara mma nke ihe ngwọta nke mmiri mmiri, viscosity nke ngwọta na-ebelata na mmụba nke ọnụ ọgụgụ shear, nke na-eme ka a na-ekesa otu ụdị nke ihe ndị dị na pigmenti, ma na-amụbakwa mmiri mmiri nke mkpuchi. .Mmetụta dị nnọọ ukwuu;mgbe ị na-ezu ike, viscosity nke ngwọta dị ntakịrị, nke na-egbochi n'ụzọ dị irè ntinye nke ihe ndị dị na pigmenti na mkpuchi.
02
Usoro ule viscosity HPMC
Otu ihe dị mkpa na-egosi iji tụọ mmetụta nrịbama nke hydroxypropyl methylcellulose bụ viscosity pụtara ìhè nke ngwọta mmiri.Ụzọ nha nke viscosity pụtara ìhè na-agụnyekarị usoro viscosity capillary, usoro viscosity ntụgharị na usoro viscosity bọọlụ ọdịda.
ebe: bụ viscosity pụtara ìhè, mPa s;K bụ viscometer mgbe niile;d bụ njupụta nke ihe ngwọta ngwọta na 20/20 ° C;t bụ oge maka ngwọta na-agafe n'elu akụkụ nke viscometer ruo akara ala, s;A na-atụ oge mmanụ ọkọlọtọ na-agafe na viscometer.
Otú ọ dị, usoro iji tụọ viscometer capillary na-akawanye njọ.Viscosities nke ọtụtụ cellulose ethers siri ike nyochaa site na iji viscometer capillary n'ihi na ngwọta ndị a nwere ọnụọgụ nke ihe na-adịghị edozi ahụ nke a na-achọpụta nanị mgbe a na-egbochi viscometer capillary.Ya mere, ọtụtụ ndị na-emepụta ihe na-eji viscometers rotational iji chịkwaa ogo hydroxypropyl methylcellulose.A na-ejikarị viscometer Brookfield eme ihe na mba ọzọ, a na-ejikwa viscometer NDJ na China.
03
Ihe na-emetụta HPMC viscosity
3.1 Mmekọrịta na ogo nchịkọta
Mgbe ihe ndị ọzọ na-agbanweghị agbanwe, viscosity nke hydroxypropyl methylcellulose ngwọta na-adaba na ogo nke polymerization (DP) ma ọ bụ ịdị arọ molecular ma ọ bụ ogologo yinye molecular, ma na-abawanye na mmụba nke ogo polymerization.Mmetụta a na-apụta ìhè n'ọnọdụ dị ala nke polymerization karịa n'ọnọdụ dị elu nke polymerization.
3.2 Mmekọrịta dị n'etiti viscosity na itinye uche
Viscosity nke hydroxypropyl methylcellulose na-abawanye site na mmụba nke ntinye nke ngwaahịa na ngwọta mmiri.Ọbụna obere mgbanwe ntinye uche ga-eme ka mgbanwe dị ukwuu na viscosity.Site na viscosity nominal nke hydroxypropyl methylcellulose Mmetụta nke ngbanwe nke ntinye ngwọta na viscosity nke ngwọta na-apụta ìhè.
3.3 Mmekọrịta dị n'etiti viscosity na ọnụ ọgụgụ shiee
Hydroxypropyl methylcellulose ngwọta aqueous nwere ihe onwunwe nke shiee thinning.A na-akwado hydroxypropyl methylcellulose nke viscosity dị iche iche n'ime 2% mmiri mmiri, na viscosity ya na ọnụego shiee dị iche iche ka a tụrụ n'otu n'otu.Nsonaazụ dị ka ndị a dị ka egosiri na ọnụ ọgụgụ a.Na ọnụ ọgụgụ dị ala, viscosity nke hydroxypropyl methylcellulose ngwọta agbanwebeghị nke ukwuu.Site na mmụba nke ọnụ ọgụgụ shear, viscosity nke hydroxypropyl methylcellulose solution na elu nominal viscosity belatara nke ọma, ebe ngwọta na viscosity dị ala ebelataghị n'ụzọ doro anya.
3.4 Mmekọrịta dị n'etiti viscosity na okpomọkụ
Ọnọdụ okpomọkụ na-emetụta viscosity nke hydroxypropyl methylcellulose ngwọta nke ukwuu.Ka okpomọkụ na-abawanye, viscosity nke ngwọta na-ebelata.Dị ka e gosiri na ọnụ ọgụgụ ahụ, a na-akwadebe ya n'ime ngwọta mmiri na-edozi ahụ na ntinye nke 2%, na mgbanwe nke viscosity na mmụba nke okpomọkụ na-atụle.
3.5 Ihe ndị ọzọ na-emetụta
A na-emetụtakwa viscosity nke ngwọta mmiri nke hydroxypropyl methylcellulose site na mgbakwunye na ngwọta, uru pH nke ngwọta, na mmebi microbial.Na-emekarị, iji nweta mma viscosity arụmọrụ ma ọ bụ ibelata na-eri nke ojiji, ọ dị mkpa ịgbakwunye rheology modifiers, dị ka ụrọ, gbanwetụrụ ụrọ, polymer ntụ ntụ, starch ether na aliphatic copolymer, na aqueous ngwọta nke hydroxypropyl methylcellulose., na electrolytes dị ka chloride, bromide, phosphate, nitrate, wdg nwekwara ike ịgbakwunye na mmiri ngwọta.Ihe mgbakwunye ndị a agaghị emetụta naanị njirimara viscosity nke ngwọta mmiri, kamakwa ọ na-emetụta ngwa ngwa ndị ọzọ nke hydroxypropyl methylcellulose dị ka njide mmiri., sag iguzogide, wdg.
The viscosity nke mmiri mmiri ngwọta nke hydroxypropyl methylcellulose fọrọ nke nta ka ọ dịghị emetụta acid na alkali, na n'ozuzu kwụsiri ike na nso nke 3 ka 11. Ọ nwere ike iguzogide a ụfọdụ ego nke adịghị ike acids, dị ka formic acid, acetic acid, phosphoric acid. , boric acid, citric acid, wdg. Otú ọ dị, acid concentrated ga-ebelata viscosity.Ma caustic soda, potassium hydroxide, lime water, wdg enwechaghị mmetụta na ya.E jiri ya tụnyere ndị ọzọ cellulose ethers, hydroxypropyl methylcellulose aqueous ngwọta nwere ezigbo antimicrobial nkwụsi ike, isi ihe kpatara ya bụ na hydroxypropyl methylcellulose nwere hydrophobic ìgwè na elu ogo nke nnọchi na steric mgbochi nke otu dị iche iche Otú ọ dị, ebe ọ bụ na nnọchi mmeghachi omume na-adịkarịghị edo, na-akwadoghị anhydroglucose unit. bụ ihe dị mfe microorganisms na-emebi ngwa ngwa, na-ebute mmebi nke cellulose ether molecules na agbụ ígwè.Ọrụ ahụ bụ na viscosity pụtara ìhè nke ngwọta mmiri na-ebelata.Ọ bụrụ na ọ dị mkpa ịchekwa ngwọta mmiri nke hydroxypropyl methylcellulose ruo ogologo oge, a na-atụ aro ka ị gbakwunye ọnụọgụ nke onye na-ahụ maka antifungal ka viscosity ghara ịgbanwe nke ọma.Mgbe ị na-ahọrọ ndị na-egbochi nje fungal, ihe nchekwa ma ọ bụ fungicides, ị kwesịrị ịṅa ntị na nchekwa, ma họrọ ngwaahịa ndị na-adịghị egbu egbu na ahụ mmadụ, nwere ihe ndị siri ike ma na-esi ísì ụtọ, dị ka DOW Chem's AMICAL fungicides, CANGUARD64 preservatives, FUELSAVER nje bacteria. na ngwaahịa ndị ọzọ.nwere ike ịrụ ọrụ kwekọrọ.
Oge nzipu: Ọktoba 20-2022